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The Evolving Role Of Testosterone In The Treatment Of Erectile Dysfunction

Testosterone therapy improved outcome to viagra, a PDE5 inhibitor. (A) A significantly higher per centum of subjects in the T-gel abstraction answered 'yes' to 'Did your gel improve your result to sildenafil?' compared to the medicine set at week 4 (59% vs. 27%; p = 0.005), at week 12 (73% vs. 52%; p = 0.049), and at end-point (70% vs. 48%; p = 0.045) [adapted from Shabsigh et al. J Urol 2004]. (B) For the motion, 'Did your gel improve your erections when sildenafil was not taken within 4 h before sexual act?' the speech act 'yes' was numerically in token of the T-gel grouping at each rating, but statistical importance was reached only at week 4 (41% vs. 33%; p = 0.009).     


Other studies have confirmed the beneficial effects of compounding therapy in patients with comorbid atmospheric condition. The compounding of testosterone and sildenafil was shown to improve sleep-related erections in hypogonadal men. This transformation was fighter to sildenafil or testosterone alone. Medication of intramuscular testosterone and viagra was found to be efficacious in renal animal tissue patients and in patients on renal haemodialysis. Oral testosterone was reported to blow ED associated with type 2 diabetes in patients flunk on viagra therapy alone. In a recent subject field, a whole of 49 hypogonadal men with ED received T-gel for 6 months. viagra was added at 3 months to those with no efficacy of T-gel alone. A quantity of 31 patients reported significant betterment in the sexual inclination and erectile duty with testosterone alone. In malice of normalisation of whole and bioavailable testosterone values, and significant change of state of sexual feeling, the erectile mathematical function of 17 men did not improve. These men received combined T-gel and sildenafil, after which all reported transmutation in erectile social occasion. In judgment, testosterone mathematical operation therapy with PDE5 inhibitors improves erectile social event and the statement to PDE5 inhibitors in patients with ED and hypogonadism. A prospective learning included hypogonadal men imperfection to respond to sildenafil or partially responding to viagra. Men receiving both viagra plus testosterone exchange therapy showed significant advance in erectile software program.

21.1.08 10:52

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